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Unlike NOX2, which primarily produces superoxide radicals, NOX4 produces H 2 O 2 which has known benefits in the cardiovascular system, such as endothelial cell growth and proliferation and regulation of endothelial barrier function [12]

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Older adults face more challenges, particularly from fine particulate matter (PM 2.5 ), since people's bodies are less able to compensate for the effects of environmental hazards as they age