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doi: 10.1016/j.expneurol.2008.04.009 71 DeuisJ

Based on the observers evaluation of these areas of the dogs body, a score is assigned from 1 (very emaciated) to 9 (obese), with a score of 45 being considered ideal body condition

As granulomas mature, they develop fibrous walls and experience a significant decrease in the number of vessels penetrating the structure, which hampers the penetration of anti-TB drugs into the necrotic and hypoxic areas of the granuloma, where M.tb persists [98, 99]

The altered MCL-1/BOK balance toward pro-death BOK has been implicated in the pathogenesis of PE 19 , although, to date, this has not been evaluated in the context of mitochondrial fission