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The significant rise in serum creatinine and urea levels following AZA administration indicated renal dysfunction, as the impaired kidneys could not effectively eliminate creatinine and urea, leading to their accumulation in the bloodstream (66)

The supplementation of leonurine into the culture medium during in vitro embryo production resulted in an enhancement of the blastocyst formation rate and total cell count, as well as cell proliferation in developing embryos