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As a result, increased stiffness triggers the translocation of the transcription factor co-activators Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) to the nucleus where they interact with the transcriptional enhanced associate domain (TEAD) family of transcription factors to induce gene expression [85]

Synthesis of Cations of Formulas I and IA The description of preparation of certain embodiments of the invention is meant to be exemplary of certain embodiments of the invention

Benson C, Mifflin K, Kerr B, Jesudasan SJ, Dursun S, Baker G.Biogenic Amines and the Amino Acids GABA and Glutamate: Relationships withPain and Depression