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It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and cysteine

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Notably, certain plant-derived metabolites activate neuroprotective signaling pathways, such as the MAPK/NF-B system, (Md et al., 2021), and interact with estrogen receptor beta (ER), a known regulator of synaptic plasticity and neuroprotection ( 4.6 Overcoming challenges in translating natural compounds into clinical applications Despite promising findings, translating the therapeutic potential of natural compounds into clinical practice presents several key challenges

China led in patent applications ( n = 39), accounting for more than half of the patents selected in this study (Figure 3)