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Consequently, long-term CM may contribute to a healthier intestinal microbiota, potentially improving gut-brain communication through multiple mechanisms, including microbiota regulation (335)

27 Thus, hypoxia-driven lactate accumulation is an exception rather than a common phenomenon, challenging the view that low oxygen levels are prerequisites for lactate production and accumulation

A strong association between CYP3A5 rs776746 with severe diarrhea ( p = 0.021) was also seen [78]

Knockout mouse models have underscored the critical role of CXCR2 in driving inflammatory diseases characterized by neutrophil infiltration and activation