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ROS affect both tumor and mesenchymal stromal cells via the collective response of all cells within the tumor microenvironment (TME)

Results Cancer cells, including melanoma, depend on de novo metabolic synthesis pathways to sustain high proliferation levels Consensus metabolic networks were reconstructed at the genome-scale for the TCGA, SKCM and IN-HOUSE datasets to capture metabolic alterations in cancer in general and in melanoma specifically

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Methotrexate: who would have predicted its importance in rheumatoid arthritis