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Description

Activation of I 1 receptors in these regions facilitates endogenous sympatholytic signaling, synergizing with the central 2 pathway to reduce blood pressure and peripheral resistance (Szabo, 2022)

PLoS ONE 2008

Furthermore, in appendiceal ligation and puncture-mediated sepsis, investigators found a decrease in GSH content and GPX4 expression and an accumulation of cardiac iron content and lipid peroxidation levels [94]