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Description

HIF Hypoxia-inducible factor (HIF) is composed of an oxygen-depleted -subunit consisting of HIF1, EPAS1 (HIF2), and HIF3, and a constitutively expressed -subunit (ARNT) [82]

Our study has important implications for our understanding of enzymatically active and inactive glutaredoxins and could be useful for the design and optimization of artificial glutaredoxins, glutaredoxin-coupled fluorescent redox sensors and transition-state inhibitors