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(Intrinsic factor is made by cells in the lining of the stomach and is needed for vitamin B12 to be absorbed.) Pernicious anaemia is the most common cause of B12 deficiency in Ireland

Causes/Risk Factors for PA and B12 deficiency pernicious-anaemia-society

For lyophilized powder, long-term storage in a freezer is generally recommended to prevent degradation

Methylcobalamin promotes the synthesis of lecithin, the main constituent of medullary sheath lipids, and increases myelination of neurons in tissue culture, more than adenosylcobalamin does