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Retrieved 3 February 2026

For instance, studies such as one on osteoarthritis (Jeon et al., 2017) have noted the re-emergence of senescent cells post-treatment cessation

16, 21 Therefore, we have undertaken extensive studies to determine the potential for BSO to enhance the anti-myeloma activity of L-PAM at clinically achievable doses using in vitro (cell lines and fresh MM explants) and in vivo MM xenografts to determine if BSO+L-PAM warrants clinical trials in MM