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The importance of mitochondrial superoxide production in APAP hepatotoxicity is illustrated by the fact that mice with a partial deficiency of manganese superoxide dismutase (SOD2) (which would usually scavenge superoxide) have exaggerated liver injury when exposed to APAP overdose [38,39]

The small intestine and liver, as the main organs for food absorption and metabolism, are particularly vulnerable to toxin damage and can affect the health, immunity, and growth performance of pigs

n = 4 mice for each genotype

Maia AS, Paga P, Delerue-Matos C, Castro PML, Tiritan ME (2020) Quantification of fluoroquinolones in wastewaters by liquid chromatography-tandem mass spectrometry