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Mechanistic model for epigenetic maintenance by methyl-CpG-binding domain proteins

In addition to the regulation of the HSP system, HSF-1 is involved in the expression of many genes under normal conditions of cell life and regulates the processes of carbohydrate metabolism, RNA splicing, apoptosis, ubiquitinylation and protein degradation, detoxification, transport of small molecules, and intracellular signaling (Neef et al., 2011