At the bioactive ingredient level, salicin B, puerarin, and astragaloside A demonstrated the strongest associations with ferroptosis-related targets (103)
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When classifying colectomy status in PSC according to i) no colectomy, ii) colectomy after sampling, iii) (sub)total colectomy or hemicolectomy at time of sampling, or iv) proctocolectomy at time of sampling, TMAO, sCD14, IL-8, LBP, ELF (all reduced) and PLP(increased) associated with colectomy status, in particular driven by those with proctocolectomy (see examples TMAO and sCD14 in Figure)
Recently, CPs potential ability to reduce endotoxemia [measured via lipopolysaccharides (LPS)] after gastrointestinal stress induced by intense aerobic exercise has been demonstrated in humans [83]