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Some evidence suggests hyperglycemic state decreases GLP-1 secretion in T2DM [39, 40]

2011 Feb 28;2(4):320-4

The M4 muscarinic acetylcholine receptor plays a key role in the control of murine hair follicle cycling and pigmentation

However, this study has notable clinical limitations: The second cohort (Cohort 2) only included 24 patients, confounding factors such as diet and concurrent medications were not adjusted for, and there is a lack of clinically standardized protocols for MDSC function detection