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Additionally, no significant differences were observed between fast and slow nicotine metabolizers in terms of the number of cigarettes smoked per day, gender, nicotine dependence score, or smoking duration

In the MR Steiger directionality test, the variance explained by included SNPs is larger in schizophrenia, bipolar disorder and anxiety compared with smoking initiation, suggesting that these observed associations might not be directionally causal

There is far, far more to this than just numbers and measurements and the sooner those of us who are generally on side with harm reduction can get those who are ideologically opposed to harm reduction (and that is *exactly* what it is, given the very strong evidence of the relative harms from e-cigs and lit tobacco there is now no excuse to claim otherwise) to stop spreading their utter crap in the press be it mendacious statistics twiddling (such as in the US, where they deliberately conflate lit tobacco which kills and smokeless tobacco of any kind which quite simply, does not), or openly lying, as recently done by a senior tobacco control wonk in Australia, where it was claimed that smoking levels in the US havent dropped but have in fact risen

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