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You need it for normal biological and physiological processes like: Biosynthesis of DNA Healthy red blood cells Maintenance of the gut mucosa and skin cells Metabolism of fat, protein, and carbohydrates Folate metabolism and the folate pathway Formation of choline-containing phospholipids Formation of succinyl coenzyme A which is needed for neural lipids and myelination Maintenance of the myelin sheath that surrounds neurons and protects against nerve damage Healthy energy levels Most water-soluble vitamins are not stored in the body and must be regularly replenished

In THMD4, mitochondrial TPP uptake is reduced but not completely abolished

MS, BA, ZU, UN, and WZ revised the manuscript

Skipping it, even with a hydrating serum, leaves your skin more vulnerable to dryness and environmental damage