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Safety Considerations Safety remains a paramount concern when evaluating new therapeutic agents

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Disclosures: Saad Aldosari: Nothing to Disclose, Sarah Alfawaz: Nothing to Disclose, Majed Almaghrabi: Nothing to Disclose, Ali Albenmousa: Nothing to Disclose, Abduljaleel Alalwan: Nothing to Disclose, Saleh Alqahtani: Nothing to Disclose, Hani Tamim: Nothing to Disclose, Karim Qumosani: Nothing to Disclose, Faisal Sanai: Nothing to Disclose 2444 PRIMARY SCLEROSING CHOLANGITIS IN AFRO-CARIBBEANS VS NON-AFRO-CARIBBEANS Ahmed Elhawary 1 Nathaniel Ash 1 Sonia Mehra 2 Bharati Dev 3 Mohammed Umair Masood 1 JAWAD AHMAD 1 Joseph Odin 4 , 1 Icahn School of Medicine at Mount Sinai, 2 Mount Sinai Hospital Morningside/West, 3 Mount Sinai Morningside/West, 4 Icahn School of Medicine at Mount Sinai (ISMMS) Background: Primary sclerosing cholangitis (PSC) is a rare liver disease characterized by multi-focal bile duct strictures and dilatation