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Influence of genetic polymorphisms on gefitinib pharmacokinetics and adverse drug reactions in non small cell lung cancer patients Cancer and Metastasis Reviews Springer Nature Link Hepatic Cytochrome P450 Enzyme Families: Drug Metabolism The liver plays a central role in drug metabolism, with the Cytochrome P450 (CYP450) enzyme system driving the oxidative transformation of countless medications and Frontiers Glutathione S Transferase P1 Protects Against Amodiaquine Quinoneimines Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics PMC

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