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Contrary to the benefits of glutamine in critically ill patients, a randomized clinical trial evaluating 1223 adult patients undergoing mechanical ventilation, with failure of multiple organs receiving high doses of glutamine (30 g/day), antioxidants, glutamine and antioxidants, or placebo, revealed that glutamine supplementation was associated to increased mortality in these individuals [72, 73]

The FDA has placed BPC-157, TB-500, CJC-1295, Ipamorelin, AOD-9604, Melanotan II, Selank, Semax, and several others on lists of substances not approved for compounding, on grounds of immunogenicity risks, peptide-related impurities, and insufficient human safety data

Neurology 100 , 4396 (2023)

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