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By integrating mechanistic, preclinical, and clinical evidence, this review seeks to position capsaicin as a plausible natural multitarget therapeutic candidate and to provide a conceptual framework for future interventions targeting the complex pathophysiology of CMS

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Anthocyanins, another important group of phenolics, can be quantified spectrophotometrically under mildly acidic conditions, with absorbance measured between 490 and 550 nm (83)

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Alzheimers disease (AD), a neurological disorder of memory loss and changes in behaviour, is associated with the accumulation of amyloid protein plaques because of the intracellular neurofibrillary tangled (NFT) aggregation produced by abnormally hyper phosphorylated tau () protein

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DOI: 10.1038/s41389-020-00285-9 Evans, R.M., Lippman, S.M

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