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Can other members of the family have CAT deficiency or be carriers

The development of highly selective or isoform-specific inhibitors will reduce side effects and is an important goal for the near future

Acetylcarnitine provides acetyl-CoA for the synthesis of acetylcholine in the brain and fatty acids in lipogenic tissues that contain fatty acid synthase, i.e., brain, liver, and adipose tissue

Relative to the 20 mL scale, key variables including column path length, residence time, and step CVs were maintained using optimized buffer conditions including a 400 mM NaCl, pH 8 wash and a 1 mM GSH, 75 mM NaCl, pH 8 elution