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*Correspondence: Michel Vignes, [email protected] Roussel, [email protected] This article was submitted to Cellular and Molecular Mechanisms of Brain-aging, a section of the journal Frontiers in Aging Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

To investigate the structural basis for the conformational changes observed in the M105I mutant, we analyzed the solvent accessibility of residue 105 throughout the refinement simulations

This review synthesizes current knowledge on the molecular mechanisms underlying ferroptosis and examines their roles in neurodegenerative disease pathology, with a particular focus on AD and PD, where ferroptosis has been best characterized

Schulze, A