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The amount of iNOS and COX2 were normalized with respective -actin level and expressed as % non-LPS control (middle panel)

doi: 10.1016/j.pharmthera.2007.09.008, 109

Cue-induced reinstatement test In the same self-administration context, the number of nosepoke into the active and inactive operanda was measured over 1 h

Together, these findings support a mechanistic dissociation in which early adversity preferentially perturbs PFC bioenergetic regulation, with comparatively weaker or distinct effects in the NAc