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These play a significant role in neurotransmitter production, inflammation control and barrier regulation and their depletion is frequently observed in individuals with depression and anxiety further suggesting their relevance to mental health (Borkent et al., 2022

Mitochondria as systemic supplements of the cardio-cerebral axis As the central organelles of energy metabolism, mitochondria play a key role as systemic regulatory factors in the highly metabolically active functional axis comprising the heart and brain

This approach includes patient education, lifestyle modifications, pharmacotherapy, and vigilant monitoring for potential complications (Garber et al., 2021)

Increased oxidative phosphorylation activity often indicates cell activation and a change in function