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The question of which B12 form is 'best' depends largely on individual circumstances, the route of administration, and the specific clinical context

Reasons why mitochondria might be impaired or damaged include: Aging Inadequate diet Poor sleep Lack of exercise Genetics Heavy and toxic metals Pollutants Free radicals Prescription drugs Alcohol There are many conditions that are caused or made worse by mitochondrial dysfunction, such as the following per Pizzorno (2014): Early aging Amyotrophic lateral sclerosis Alzheimers disease Autism Cardiovascular disease Chronic fatigue syndrome Dementia Diabetes Huntingtons disease Migraine headache Parkinsons disease A great way to directly influence the health of our mitochondria is through the use of peptides

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So a tiny little needle, and it needs to be near the site of injection, not right on the site of injection, because that where the, I mean, site of injury, not injection