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Given the widespread and unregulated use of e-cigarettes, especially by youth and other vulnerable populations, further studies are needed to evaluate both the acute safety and long-term health risks of using alcohol-containing e-cigarettes, said Mehmet Sofuoglu, of Yales Department of Psychiatry and VA Connecticut Healthcare system, who is senior author of the paper

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Additionally, smoking was associated with a significantly increased risk of IBS-diarrhea, while this only applied to the highest exposure category (20 or more cigarettes per day), there was a trend for a dose-response relationship