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The studies characteristics, criteria for assessing clinical effectiveness rates, interventions, outcomes and the names of Chinese medicine decoction prescription are provided in Supplementary Tables S3S8

3.2 DNA fragmentation In addition to lipid peroxidation, oxidative stress induces significant damage to sperm DNA, leading to DNA fragmentation ( Figure 2 )

Recent evidence suggests that reduced free radical scavenging enzyme activity such as glutathione-S-transferase (GST) activity may have role in the development of this condition