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Pomegranate-derived compounds have been shown to modulate a wide range of molecular targets, including transcription factors, pro- and anti-apoptotic proteins, cell cycle regulators, protein kinases, cell adhesion molecules, pro-inflammatory mediators, and growth factors across multiple cancer types, such as skin, breast, prostate, colon, and lung cancers (366, 367)

La matire premire possde le Certificat FSSC 22000, le Certificat de qualit MSC (soutient la pche durable), le Programme Responsible Sourcing Audit (pche thique), ainsi que des certificats de casher et Halal

284 MAT2A Methylthioadenosine phosphorylase (MTAP)-deficient tumors account for ~15% of solid tumors, including ~15% of NSCLC, 28% of esophageal cancer, 26% of bladder cancer, and 10% of esophagogastric cancer

Statements Author contributions CL and GK participated in the design, writing, and final corrections of the manuscript