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However, when GPX4 is inhibited or glutathione levels are depleted, lipid peroxides accumulate unchecked, initiating ferroptosis (Kalluri, 2016

doi: 10.1038/nature25509 231 ZhaoJ.DavisM

The correlation between striatal glutamate levels and the severity of social deficits aligns with the role of the striatum in social behavior

That dual approval reflects the compound mechanism of action, which treats weight and metabolic health as interconnected problems rather than separate issues