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On the other hand, GST is more widely used in downstream applications compared to MBP

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Fengming Luo is one of the Associate Editors of Signal Transduction and Targeted Therapy, but he has not been involved in the process of manuscript handling

Conversely, other studies propose that while excessive HO-1 activation might protect against heme-induced oxidative damage, it may also trigger atypical ferroptosis by generating excessive free iron through heme degradation ( Figure 4 )