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HyPer7 responses confirmed the cell cycle and metabolic cycle-associated H 2 O 2 cycles that we previously reported, based on roGFP2-Tsa2C R sensor responses 34,35

The crystals were then flash-frozen in liquid nitrogen, and data were collected at the Diamond Light Source beamlines I04 and I04-1 and processed automatically using the Xia2 Dials pipeline 53,54