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Targeted Therapy for Non-Small Cell Lung Cancer

Recent single-cell RNA sequencing (scRNA-seq) studies (287, 288) have further revealed that in CKD, PT cells downregulate SLC7A11 and GPX4 expression, while interstitial fibroblasts upregulate pro-ferroptotic genes (e.g., ACSL4 and LOX), suggesting cell type-specific ferroptosis programs that drive fibrosis

These secreted factors attract and activate inflammatory cells, such as neutrophils and macrophages, to the site of injury (Liang et al., 2025)

This systematic literature review expands upon VA's previous review by comprehensively integrating data from multiple evidence streams (ie, epidemiologic, animal toxicological, and mechanistic data) to identify adverse neurologic, as well as cognitive and behavioral health effects following jet fuel exposure