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The ERK1/2 branch drives proliferation via growth factor receptors and K-Ras (Khavari and Rinn, 2007)

(ii) structural descriptors (BET surface area with micropore/mesopore distribution by NLDFT, heteroatom content and bonding configuration by high-resolution XPS)

Additionally, plant metabolites and derivatives can regulate ferroptosis by targeting SLC7A11, GPX4, and ACSL4 and influence the immune status in the tumor microenvironment, providing new insights and directions for TCMs in cancer treatment