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A brief introduction to each of these different classes of antioxidants follows

doi: 10.1002/14651858.CD006316.pub3 53 SumitaniMTochinoYKamimoriTFujiwaraHFujikawaT

As their classification suggests, the side chains tend to be repelled from water, so this impacts the positioning of these amino acids in the protein tertiary structure

The molecule is structurally modified with an N-terminal trans-3-hexenoyl group, which dramatically reduces its susceptibility to dipeptidyl peptidase IV (DPP-IV) degradation, the enzyme that breaks down natural GHRH