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The reasoning is that oral bioavailability is ~4050%, and animal study HED conversions suggest higher doses may be needed for the full effect

Saydah S, Ballard-Barbash R, Potischman N

They can evaluate you, look at a blood sample, and determine whether you have a deficiency

It plays a vital role in the healthy functioning of many systems in the body, including the following: DNA (genetic material) synthesis Energy production (metabolism) Nerve cell health Neurological (brain) function Red blood cell (hemoglobin) formation Vitamin B12 plays a key role in the normal functioning of the brain and nervous system