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Discussion Failure in maintaining the intricate cellular organization and multidirectional interactions of the cells within the liver leads to chronic disease, often presenting with cholestasis and fibrosis, which progresses to cirrhosis and cancer 53,54

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doi: 10.1016/j.carbpol.2021.118921 129 XieSZLiuBYeHYLiQMPanLHZhaXQet al

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TP53 induces ferroptosis primarily by transcriptionally repressing the expression of SLC7A11 (Le et al., 2015

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