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Once the triggering stress stabilizes, whether from nutritional optimization, weight loss stabilization, or both, follicles re-enter the growth phase

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Elevated IL-6 and TNF- concentrations in CMS exposed mice demonstrate stress-induced inflammatory signaling contribution toward anxiety-like behaviors (Tyagi et al., 2025)

Although CD38 high NK cell population is reduced by CD38 mAb, it brings few destructive effects to the efficacy and safety during combined therapy, because IMiDs, such as Lenalidomide, markedly enhance NK cell-mediated ADCC by increasing the number and activity of activated CD16 + NK cells [71, 98, 101]