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1 The remaining trace amount of CHAPS were base line separated from the analyte with the optimized HPLC condition and prevented from getting into the MS system by applying the scheduled ionization feature in Analyst software 1.7 (Figure 1)

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In premenopausal women, there is significant interest in whether supra-physiological concentrations of estradiol, as found in combined hormonal contraceptives (CHC), impact womens weight (237)