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Description

Peptide bond formation joins amino acids through a nucleophilic attack of an -amino group on an activated -carboxyl carbon, releasing water and forming an amide (peptide) bond with partial double-bond character due to resonance delocalization of the nitrogen lone pair into the carbonyl

10.1016/j.antiviral.2017.12.015 93

3,3-Dimethyl-1-butanol (DMB) was shown in animal models to inhibit TMAO production and attenuate EC dysfunction, positioning it as a promising candidate for preventing vascular damage driven by microbial metabolites [267]