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Description

Microbiome 6 , 104 (2018)

These findings provide a theoretical framework for identifying novel, symptom-specific therapeutic targets for pharmacological intervention

Core metabolic disturbancesoxidative stress, mitochondrial dysfunction, and hypoxiainitiate neurological damage, while the hormonal system, centered on the HPA axis, amplifies and coordinates these effects

Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY