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doi: 10.1016/s0197-0186(00)00031-0

Chernausek SD: Insulin-like growth factor-I (IGF-I) production by astroglial cells: regulation and importance for epidermal growth factor-induced cell replication

Its deficiency is implicated in several serious health conditions, and understanding these connections can inform research priorities and protocol design

Remember, B12 is needed for this cell to mature, so with insufficient B12 megaloblasts accumulate in your bone marrow and large red cells called macrocytes appear in your blood