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Heres a list of potential causes: Smoking and vaping Sun exposure Drinking from a straw or bottle Repeated facial expressions Pouting/smiling Playing musical instruments (like the recorder or harmonica) Genetics Lifestyle factors Among these, smoking, including vaping, is one of the primary factors leading to vertical, fine lines and wrinkles appearing around the mouth

From lung damage and heart disease to premature aging and mental health struggles, the consequences of smoking are too severe to ignore

In 2018, 0.3% of high school students who used e-cigarettes reported buying the products from a vending machine at an airport

The characteristics of the study population and smoking status by sociodemographic characteristics are summarized in Supplementary file Tables 1 and 2