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During implantation, embryo-maternal crosstalk takes place, and structural and functional alteration of the endometrium and uterine space result in an optimal embryo implantation ( Tissue engineering uses a mix of cells, biomaterials, and engineering technologies to fix and substitute damaged tissues, as well as preserve and restore the functionality of tissues following injury (Taymour et al., 2024)

Our study also found that NRF2, GPX4 and SOD1 expression levels were higher in the neoadjuvant chemotherapy-resistant group compared to the sensitive group, further supporting our hypothesis and demonstrating the adverse effects of GSH on chemotherapy in breast cancer patients

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