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To fabricate the PEO-CS-LEV/PLGA-QS core-shell nanofibers, the PEO-CS-LEV and PLGA-QS solutions were poured separately into two 5 mL plastic syringes connected to the coaxial spinneret of a co-axial electrospinning set-up (Fanavaran Nano-meghyas, Iran) and were electrospun under optimized electrospinning conditions including the collecting distance of 15 cm, applied voltage of 15 kV, and feed rate of 0.6 mL/h (core solution) and 1 mL/h (shell solution)

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We described the functions of melatonin as a mitochondrial protector in an earlier section