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Evidence from observational and Mendelian randomisation studies suggest an effect of smoking on both depression and schizophrenia (see section 2.1 and 2.2)

Electronic cigarettes are a relatively new product on the market, so several package designs were necessary during the initial stages when it was completely unregulated

In 2011, FDA issued an ANPRM regarding remote sales and distribution of tobacco products, 233 but has not taken further regulatory action since that time

The structured methodology of the model facilitates comprehensive trend characterization across multiple temporal segments, allowing for the quantification of disease prevalence and burden trajectories