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visnaga exhibited a significant cytotoxic and apoptotic impact on human liver cancer cell lines (HuH-7) and inhibitory effects on HeLa (cervical cancer) and breast cancer (MCF7) cell lines [211]

Klipstein-Grobusch K, Grobbee DE, den Breeijen JH, Boeing H, Hofman A, Witteman JC

Results: The study population included 143,310 patients with a diagnosis of NAFLD and at least one associated liver complication

The peptide itself was first identified in human plasma in the early 1970s, and the copper-bound form was recognized shortly afterward as the biologically relevant species in many of the contexts where the tripeptide's activity was characterized