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X.et al (2022c)

2.9 Statistical analysis All numerical values and graphs are displayed as mean standard error of the mean (SEM) unless otherwise stated

Importantly, circulating HTY metabolites, mainly HTY sulfate and HTY glucuronides, reach plasma concentrations several-fold higher than parent HTY and retain cardiovascular-related bioactivity

When amitriptyline is given with anticholinergic agents or sympathomimetic drugs, including epinephrine combined with local anesthetics, close supervision and careful adjustment of dosages are required