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Clusters of cells sharing similar transcriptomic signals were initially identified using the Louvain algorithm, and clustering resolutions varied between 0

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Thymidine analogs have additionally been shown to cause cell senescence through an increase in oxidative stress and induction of mitochondrial dysfunction in human fibroblast cell lines and in subcutaneous adipose tissue from HAART patients ( Protease inhibitors also have the potential to induce oxidative stress, although it is not always clear whether PI induced elevated ROS is produced at the mitochondrial level

Boelen A, Kwakkel J, Alkemade A, Renckens R, Kaptein E, Kuiper G, et al