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After oral administration, collagen-based supplements transit across the intestinal epithelium via transcellular and paracellular transport, followed by secretion into the lymphatic system or bloodstream of a substantially non-degraded therapeutic, requiring the circumvention of multiple structural and functional barriers (Fig

Particularly for disc-derived stem cells (e.g., NP-MSCs), moderate hypoxia (e.g., 2% O2) may be beneficial for maintaining their stemness and bioactivity, but further research is needed to clarify the optimal conditions and mechanisms

Blood Acylcarnitine Levels in Normal Newborns and Heterozygotes for Medium-Chain Acyl-CoA Dehydrogenase Deficiency: A Relationship between Genotype and Biochemical Phenotype? Journal of Inherited Metabolic Disease , vol